Cell Research Associate - London

Posted 24 January by CK GROUP
Jason Johal is currently recruiting for an Associate Scientist to join the Cell Research team of a new immunotherapy company that has been seeded by an international investment group dedicated to life sciences and has also received support from Cancer Research Technology, King's College London and the Francis Crick Institute. Offered on a full time permanent basis, the role will be based in a brand new facility in London and comes with a salary of £25,000 - £35,000 plus benefits.

The company is being incubated in London as it has become a global hub for cell manufacture and has been founded on pioneering research into gamma delta T cells. The group are focused on exploiting this work to develop improved immunotherapies for cancer and potentially other diseases and plan to exploit unique properties of tissue resident gamma delta T cells for effective immunotherapy.

They have developed proprietary methods for the extraction and amplification of gamma delta T cells from particular tissues to levels where they can actually think about therapy and nobody else can do that. These cells, when analysed tick pretty much every single box you want for a potent and it is this that differentiates their research from other approaches to immunotherapy being pursued. This has the potential to make a significant impact on the treatment of cancer especially combating solid tumours & leukaemia.

This role will support the in vitro and in vivo detailed characterisation of tissue resident gamma delta T cells. The work will examine the growth, regulation and function of these cells such that optimal and scalable growth conditions can be established and their unique killing properties and interactions can be optimised and exploited.

Your main responsibilities in this role will be to:
• Conduct Primary Cell Culture of skin derived gamma delta cells, starting from human tissue
• Maintain & manage cell cultures, including gamma delta cells from different tissue sources and other cell lines as required
• Prepare experimental plans to screen for optimal cell isolation and culture conditions for agreement with supervisor and conducts agreed work
• Conduct phenotypic and functional analysis of cells according to experimental plans.

This will include cell counting, cell viability and flow cytometry analysis
• Examine conditions for cell storage, including the impact of freeze-thaw
• Participate in lab management, including managing and coordinating consumables and shared materials to enable the smooth running of the laboratory

In order to be considered for this role, you will be required to have the following qualifications, skills and experience:
• Experience working with cell culture in an academic or industrial setting (previous experience with primary cell culture preferred)
• Experience of working to high health and safety standards with previous knowledge/experience of GMO, HTA or GMP regulations an advantage
• Experience of techniques such as Elispot, PCR, cytotoxicity assays, cell-based functional assays and immunoassays
• A BSc in a relevant scientific discipline (such as Biology) or substantial equivalent laboratory based previous work experience

If successful you will be joining a company at the cutting edge of research and will have access to truly exciting science and a different approach to Immuno-Oncology. You will be working with “World Class” scientists with a pedigree built from experience and credibility on a fast schedule to clinical translation and eventually the market.

Please note that your CV should show exact dates of employment (month and year) and any gaps of a month or more should be explained.

CK Group is an Equal Opportunities employer and welcomes applications from all who meet our selection criteria.

If you do not hear back from us within 5 working days of your application for this role, it means that on this occasion you have not been shortlisted for the next stage of the recruitment campaign. Entitlement to work in the EEA is essential. Please quote reference ST41125 in all correspondence.

Reference: 34312707

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